Skip to main content

Montelukast :Use,side effect ,dosage,action,Price

Use of Montelukast

Montelukast is mainly used for treatment of asthma ,exercise-induced bronchospasm
Allergic Rhinitis,(it is also known as hay fever, is the type of inflammation in the nose which
Is the overreact to allergins.

Asthma is a condition cause by inflammation in the airways. Though it may not a serious problem for some, it can be lethal to others, and the inflammation involved brings many discomforts to all who experience it. The muscles in the airways get irritated and begin to constrict. Airways will be then become more and more narrow resulting in difficulty passing airflow in and out of the lungs. Symptoms of asthma such as wheezing, chest tightness, and shortness of breath will soon follow. In addition, the inflammation causes the lining of the airways to produce more mucus which then leads to coughing.

 Montelukast is come under the leukotriene this category one another drug is Zafirlukast has the same action.
Montelukast tablets
montelukast tablets

Asthma symptoms may come from time to time depending on the daily activities of the person experiencing it. Some people can trigger an asthma attack through exercise, fumes, or pollen. These things cause the body of the asthmatic person to produce a chemical substance called leukotrienes. Leukotrienes are the main reason for the inflammation of the airways. Montelukast 10 mg is a great medication that helps control the symptoms of asthma.What is Montelukast?

Montelukast is a leukotrienes receptor antagonist that helps get rid of asthma symptoms. It is available in different dosages but among the most common is montelukast 10 mg. It also comes in different brand names like Singulair. However, montelukast generic forms are also available. Customers have the freedom to choose between the branded montelukast 10 mg and the generic. But just a little information from the makers of montelukast … it usually works after 3-14 days after the start of medication therapy, and therefore it is not used as a treatment for an acute asthmatic attack.

Side effect of Montelukast and zafirlukast

These two drug are very safe drug having very less side effect like
Headache and rashes.
Suicidal thought or action
Sleeping trouble
Eosinophilia and neuropathy are infrequent.
Some case of church Strauss syndrome has been reported.
Montelukast and zafirlukast are well absorbed orally ,highly plasma protein-bound and metabolized by CYP2C9, CYP2C8 and CYP3A4.
The plasma half-life of montelukast is 3-6 hours , zafirlukast  is 8-12 hour.
Some brand name of montelukast is EMLUKAST,MONTAIR,VENTAIR 4 mg ,5 mg,,10 mg tablets,ZUVAIR  10 mg ,20 mg tablets.

Action of montelukast

Asthma is mainly occour in morning and evening. Asthma and chronical obstruct pulmonary diseases are mainly same but asthma has main three Problem is also called triangle problem of asthma.
1 airway obstruction
2 smooth muscle hyperplasia
3 inflammation
Asthma has two action immediate action and late phase action
Type of asthma is two type
1 Atopic /Extrinsic
2 Non atopic /Intrensic
Non atopic is case which is cause by aspirin, Exercise, stress, cold, occupational toxic

Bronchial asthma is occours due to cystenyl leukotrienes(LT-C4/D4) for that reason leukotriene antagonists are develop.

CysLT1 receptor is responsible for  broncho constriction , increased vascular permeability and recruitment of eosinophil .
Bronchodilation ,reduced sputum eosinophils count ,suppression of bronchial inflammation and hyperreacctivity are noted in asthama patients.
Some studies have found that certain patients are responders while other s are nonresponders to anti-LT therapy.

Drug interaction of Montelukast

This drug has very few drug drug reaction.

So doctor prescribe the combination of motelukast  with a CYP2C8 substrate like
Amodiaquine or antimalarial drug could increase the  plasma concentration of the substrate .
Dosage of montelukast
What is montelukast ?
Montelukast is medicine which is available in the market as tablet, chewable tablets, granules, liquid .
Montelukast brand name of the tablets is singulair which is prepare by merck & co.
This medicine is not stable as its own molecule so it made as salt form.
Doctor mainly given the montelukast with adding some other drug.
Levocetirizine is mainly added with montelukast.

History of Montelukast

There is no information about the history of montelukast.

Dosage of montelukast

Montelukast is available in generic form and brand form.
Oral tablets are made 10 mg and chewable tablets are made 4 mg and 5 mg of strength.
For asthma treatment
Of above the age 15 year 10 mg once daily in the evening.

For age 2-5 year 4 mg chewable tablet once daily in the evening.
Pataint which is suffer exercise-induced bronchoconstriction they are taking the montelukast before 2 hour of exercise.
Montelukast is used only once per day if suffer multiple.
Donot stop the taking of the drug suddenly. if you suffer asthma.
Take the dose timely and the daily basis for proper working of drug.
If you take more drug it may cause overdose some symptoms are

  • pain in your abdomen
  • vomiting
  • trouble sleeping
  • thirst
  • headache
  • hyperactive behavior
Storage condition of montelukast is Room temperature.
The recommended dosage is one pill once a day daily for adults using montelukast 10 mg. Children, on the other hand, are not advised to take montelukast 10 mg tablets because the dosage is too high for them. Instead, they use lower doses like a 4-5 mg tablet each day.
However, given the fact that not all medications are suitable for everyone – especially if they are having special health conditions – taking montelukast 10 mg should only be done after consulting with your doctor first in order for serious health complications to be avoided. Don’t forget to tell your doctor if you have one of the following conditions:
• Pregnant or trying to become pregnant
• Breastfeeding
• Using other medications such as herbal or complementary medications
• If you have an allergic reaction to any of the ingredients found in montelukast 10 mg.


Popular posts from this blog

Clozapine Tablets: Use, Side Effects and Mechanism Action

Clozapine Use For SchizophreniaClozapine is very effective medicine for the treatment of psychosis symptoms also know as neuroleptics. Clozapine is not a single medicine use for the treatment of psychosis. This drug is classified as atypical antipsychotics.
This medicine is used as a reserve drug in refractory schizophrenia that means when other medication-related to schizophrenia are not working that time clozapine is show there an action for the treatment of psychosis.
This medicine are use treatment-resistant schizophrenia that means those patients are fail to the treatment of schizophrenia. Doctor recommended this drug to that patient who fails to treatment with other medication.
This Drug is also used for the reduction of suicidal behavior in schizoaffective disorder. Schizophrenia disease suicidal behavior is one stage. Patient want to kill himself so that patient are kept in watch.
One study conducted to proof the action of this drug as compare with olanzapine and results are foun…

Nifedipine use, Side Effects, Mechanism of action, Dosage and Adverse effect

What is Nifedipine? Nifedipine tablets belongs to the group of medicines called calcium channel blocking agents. IUPAC name of this drug is dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate. This drug is yellow in color and crystalline powder and insoluble in water.

Contents What is Nifedipine?Nifedipine useNifedipine Side EffectsMechanism of actionPharmacokinetics of nifedipine Adverse effects of NifedipineDose of nifedipine Nifedipine use Nifedipine tablets is a calcium channel blocker that blocks calcium to the muscles wall of the heart, allow the muscles to relax and widen to increase blood flow to the heart; making it easier for the heart to pump and function properly. Nifedipine is widely used to treat
High blood pressure
Chronic stable angina
Ruptured aneurysm (a problem caused by a burst blood vessel around the brain) Early labour for pregnant women Raynaud’s phenomenon Anal fissures High altitude pulmonary edema Spasms of esophagus due to cance…

Risperidone side effect, mechanism of action,use

Risperidone side effect, mechanism of action, use
What is Risperidone?
Risperidone is medicine use as antipsychotic treatment. Antipsychotic diseases like Schizophenia, bipolar disorder, autism . How to take risperidone Before taking of this drug must read the manual or leaflet which is present along with this medicine. if you are not comforted with this then take the advice of doctor or pharmacist. It is also used for the treating of obsessive-compulsive disorder .in this disease patient are doing the one work repetitively. It also helpful for dementia. But FDA does not approve for the treatment of dementia.

The doctor always prescribe the drug for beater effect of in the patient or cure the patient if you have side effect occurs or any discomfort with this drug contact with your doctor immediately. RISPERIDONE SIDE EFFECT Mainly common side effect are shown movement problem, sleepiness, seeing a problem, constipation, increased weight .serious side effect permanently movement problem othe…